9 Favorite Cannabis Strains of All Time

Cannabis has arguably been one of the most popular plants on the planet for centuries, and while there have been hundreds upon hundreds of different cannabis strains created, some stand-out more than others. 

Whether because of their flavor or high potency, these nine cannabis strains are some of the most memorable in history, providing users with an unforgettable experience. From Sativas to Indicas and everything in between, each adds a unique twist on marijuana that stands out. 

If you are a cannabis enthusiast, you know that there are various strains with different flavors and effects. With the wide selection of choices on the shelves today, it can be challenging to weed out the ones that don’t entirely cut. 

To save you some time and trouble, we have chosen nine of our favorite strains that have stood out to us as some of the hottest. From potent Indicas to powerful Sativas, delve into this list of renowned genetics and discover why connoisseurs favor each one.

Most Popular Cannabis Strains 

Consuming the same strain can get boring, so why not switch it up? Farmacy District is a true cannabis connoisseur’s dream, providing some of the most sought-after strains worldwide. The following are nine of our favorite strains specially chosen for their unique flavor and effects.

  • Blue Dream Strain

The Blue Dream strain is famous for cannabis enthusiasts worldwide, but what keeps it at the top of many people’s favorite lists? The answer lies in its balanced effects. 

Created by blending Haze genetics, Blue Dream is a hybrid strain that provides an uplifting, euphoric experience and has calming qualities that make it perfect for use before hitting the hay or taking a break from stress.

Its buds come with a sweet, fruity taste and an aromascape blended with blueberries with undertones of lavender flavor. With THC content ranging between 18-24%, you know you won’t be disappointed with this classic go-to strain. [1]

When consumed, Blue Dream delivers many positive effects, from euphoria to creativity and relaxation. Its citrus aroma helps balance the mind and body, making it an ideal strain for day or night use.

  • Girls Scout Cookies Strain

Girl Scout Cookies have been a favorite cannabis strain among smokers for years. It’s an Indica-dominant strain that presents a mix of sweet and earthy aromas with hints of pine, perfect for casual gatherings or solo indulgence. 

These buds boast a dense, crisp texture and are laden with frosted glaze. A little toke from these GSC buds brings a signature icy mint flavor, as though you were inhaling snowflakes. 

Undeniably, Blue Dream and Cookie strains almost always come up when discussing the most popular weed. In social situations, they can have uplifting effects while effectively relieving stress after long days at work or school. That’s why experienced users would easily name Girl Scout Cookies as one of their favorite cannabis strains. 

Comprised of roughly 60% Cannabis indica and 40% Cannabis sativa, Girl Scout Cookies flowers typically harbor an impressive 19-20% THC content, trace CBD levels, and possibly 1% CBG. [1]

  • Dutch Treat Strain

Split bill is a Sativa-dominant strain famous for its fruity flavor with citrus and pine notes. Its flowering buds are coated in abundant resin and carry an earthy aroma. It has a THC content ranging from 15 to 22%, making it one of the more potent strains on this list. [2]

Regarding effects, Dutch Treat is known for delivering an uplifting and calming high. This strain has become a favorite among cannabis enthusiasts looking for a smooth smoke that leaves them feeling relaxed and focused. 

The combination of its potent THC levels and terpenes make Dutch Treat an excellent choice for those who need relief from anxiety or depression without the sedative effects that come with most indica strains.

  • Cheese Strain

The Cheese strain is an Indica-dominant hybrid that’s been around for decades. It was created as a cross between two classic cannabis strains, Skunk and Afghani landrace. Its buds are dense and sticky and feature hues of purple and pink. 

Cheese has a subtly intense aroma with tangy cheese notes and sweet berries. On the exhale, it’s a complex blend of sweet, sour, and earthy flavors. Cheese’s high THC content, which ranges from 15 to 20%, sets it apart from other strains. Its heavy dosage of cannabinoids makes this strain ideal for those looking for an intense body-high or restful sleep. 

The mix of relaxation and euphoria makes it a popular choice for those who need relief from chronic pain or stress. It’s also a great go-to strain for beginners looking to dip their toes into the world of cannabis.

  • Pineapple Express Strain

The Pineapple Express strain is a classic favorite amongst cannabis connoisseurs. Combining a Trainwreck and Hawaiian plant, this sativa-dominant hybrid resonates with many marijuana fans. With its uplifting, euphoric effects, the Pineapple Express strain provides a pleasant feeling of invigoration and creativity while providing a unique taste profile to the experience. 

The results can vary depending on the specific plant used during cultivation, so choosing the right bud is critical. Don’t worry if you don’t want something too strong; plenty of high CBD/low THC varieties will give you enough of that heady sensation without overwhelming you with their potency, a total win.

  • Trainwreck Strain

Trainwreck strain is renowned for lifting users’ spirits and bringing euphoria. Doctors often recommend it because it has a high THC content, meaning it can be used as medicine and recreational. 

Also, its higher CBD/low THC ratio makes it less likely than other types to cause lightheadedness due to its potent psychoactive properties. That’s why the Trainwreck weed strain is one of the most sought-after cannabis strains of all time; when you need relief from both physical pain and mental stress, this strain will always do the trick. 

Sometimes it may be hard to find, but when you come across some Trainwreck flower buds, you know what you’re getting is special.

  • Blueberry Muffins

The Blueberry Muffins strain is a balanced hybrid that takes after its Indica parent, Blueberry. Its buds are colorful and feature purple, green, and blue hues with an earthy aroma. This strain has a THC content ranging from 16 to 18 percent, and it’s known for delivering a pleasant body high that will keep you calm and relaxed. 

The effects of Blueberry Muffins also have a significant cerebral component, which is perfect for those looking for a balanced high that won’t leave them feeling too tired. It’s also reportedly an effective remedy for pain, nausea, and insomnia. 

With its fruity taste and unmistakable aroma, Blueberry Muffins is a great strain for those looking to enjoy their cannabis without the overwhelming effects of other strains.

  • Gelato Strain

The Gelato strain is an Indica-dominant hybrid quickly becoming one of the most popular weed varieties. It was created in California by crossing Thin Mint Girl Scout Cookies with Sunset Sherbet. Its buds are frosty, dense, and covered in a trichome coating that shimmers in the light. 

With its sweet aroma of blueberry muffins, the Gelato strain has an overwhelmingly pleasant smell that will tantalize your senses. It also features THC levels ranging from 18-22%, making it an incredibly potent strain. [3]

Gelato’s effects are calming and euphoric, which makes it perfect for those seeking relief from stress, pain, or insomnia. It’s also said to help promote clarity and creativity in its users, making it an excellent choice for those looking for an uplifting experience.

  • OG Kush Strain

From its unmistakable aroma to its potent effects, OG Kush is one of the most popular and beloved marijuana strains worldwide. It’s a hybrid strain created from a cross between a Hindu Kush plant from Afghanistan and an Indica plant from Northern California.

Its buds are incredibly dense and feature many bright orange hairs with hints of green throughout. OG Kush strain has a unique scent described as earthy and skunky, with some sweet citrus notes on the taste. It packs a punch in terms of its THC content, ranging from 18-23%. [2]

Thus strong effects tend to be felt quickly, leaving users relaxed and sedated. This strain is excellent for chronic pain, stress, or insomnia patients who want a quick-acting remedy.

Farmacy District’s strains are carefully selected from the highest quality sources, so you know you won’t be disappointed. Whether you’re looking for a strain to ease your pain or one that will give you an uplifting experience, Farmacy District has something for everyone. From Girls Scout to Gelato and everything in between, something in our selection will make your day a little brighter. Stop by today to get a better look at our selection and find the perfect strain for you. Contact us with any questions, and we’ll gladly help you pick the perfect strain. You won’t regret it!


1. What are the most popular cannabis strains of all time?

Blue Dream and Girl Scout Cookies are two of the most sought-after cannabis strains, renowned for their remarkable abilities to induce feelings of joy and euphoria while calming your nerves when used before bed.

2. What strain is best for studying?

Lemon-based cannabis varieties generally offer a clearheaded and brisk sativa experience (or an energetic mix). Combining this with the alertness that “Haze” family strains are known for, it is no surprise why Lemon Haze, as well as its descendant strain Super Lemon Haze, have garnered acclaim for supplying a jolt of energy and attention ideal for studying.

3. How are strains grown?

To create a distinct strain of cannabis, female plants must be pollinated with male pollen via controlled selective breeding. To cultivate marijuana for medicinal or psychoactive properties specifically, separating the males from the females is essential.